<p>The present book covers estrogen, its receptors and estrogen mediated gene regulation in the brain. Further, it explains the mechanism of estrogen action and dysfunction leading to diseases. Briefly, estrogen mediates its multiple functions in the brain through two well-characterised receptors: ER&#945; and ER&#946;. Upon binding with estrogen, ER recruits coregulators, which are responsible for tissue specific regulation. When coregulators activate the transcription of a particular gene, they become coactivators; when they repress the activity of particular gene, they are called corepressors. These coregulators make a bridge between the basal transcription machinery and the receptors by protein-protein interaction. Estrogen disrupters are also explained in this book. Furthermore, the role of estrogen and its receptors are explained in the context of aging. Taken together, this book shall be self-explanatory concerning estrogen action in the brain in various aspects. Therefore, it is intended for researchers interested in the aforementioned aspects.</p>

A Handbook on Estrogen Receptors in the Brain (Neuroscience Research Progress)

Medical Books

Paramanik, Vijay

Medicine

Nova Biomedical

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Books by Paramanik, Vijay

See the best price to sell, buy, or rent books by Paramanik, Vijay. BookScouter helps to compare book prices from 25+ online bookstores and 30+ buyback vendors with a single search.

A Handbook on Estrogen Receptors in the Brain (Neuroscience Research Progress)