Needle biopsy of the liver is now an accepted procedure in most  large hospitals, and surgeons and laparoscopists are more likely to  biopsy the liver under direct vision than in the past. Consequently,  increasing demands are being made on pathologists for rapid diagnosis.  This full colour atlas provides a practical guide to the  histopathological diagnosis of liver disorders, with particular  emphasis on clinicopathological correlation and the need for the  pathologist to be in full possession of all the available clinical  information. Although containing over 350 colour illustrations, the  book is more than just an atlas and each section includes a brief  description of the main clinical and pathological features of the  subject under discussion.  For this second edition, many chapters have been rewritten - e.g. on  viral hepatitis - and many new illustrations added. The book is  intended for the practising and trainee pathologist and the clinician  who performs liver biopsies, but will also be of value to  postgraduates, residents and students in other branches of medicine.

Atlas of Liver Pathology (Current Histopathology)

D. G. Wight

Health, Fitness & Dieting

Springer London

The past few years have seen the publication of a large number of articles and not a few books on the subject of relief of intractable pain. New ideas have been put forward on pain mechanisms, new methods of treatment have been reported and improved results c1aimed, and a growing catalogue of complications oftreatment has been recorded. The vast and expanding literature on the subject poses for the reader the dual problems of surveil lance and of assessment. The object of the present book is to provide a critical and constructive review of current writings and ideas on a wide range of aspects of the nature of intractable pain, particularly of present day practice and new ideas on treatment. Each chapter is written by an acknowledged authority and the approach throughout is practical rather than academic. In editing the individual chapters an effort was made to achieve a contemporary approach and to eliminate material which was unduly historicalor retrospective in content. At the same time the individ ual style of the authors was retained as far as possible. For decades chronic pain has been a therapeutic 'no man's land'. For the surgeon pain was an unfortunate complication wh ich not infrequently followed surgery; for the physician it was a distressing symptom in a number of disease syndromes; to the psychiatrist it was one of a number of features in many cases of mental illness.

The Therapy of Pain

Mark Swerdlow

While this book is concerned with psychology let no reader believe that after studying it he or she will be a budding psychologist. Only those elements of psychology which are central to the adequate functioning of the professional in the health and allied caring services are covered. Many popular topics, such as intelligence, memory, concept formation, will not be found within the covers of this book. The objective of this book is to enable those professionals who have responsibility for the wellbeing, health, and care of others to develop insight into and to become more empathetic to the needs, motivations, feelings and behaviour of their charges. An ancillary objective is that the readers too might come to understand a little more about their own behaviour, particularly in relation to their work situation. Patients in hospital, children in residential care, the elderly in the old folks' home are all perceiving and thinking organisms, not merely interesting medical cases, a classical set of symptoms, a collection of statistics or a bulging case file. Every person whether professional or client is affected by the way others respond to them, by the feelings each has for the other, by the non-verbal signals of eye contact, smile, and voice tone, etc.

Essential Psychology

R.B. Burns

Psychology & Counseling

Throughout the history of mankind from primitive man to the present time, vitamin ddiciencies have been a major cause of death and disease. Pellagra, scurvy and beri-beri have decimated armies, ships' crews and even nations (Figure I). As late as 1925 the disease 'pernicious' anaemia caused by the ab­ sence of vitamin Bl2 within a person's body really lived up to its name. Although there were isolated instances of recognition of dietary deficien­ cies even a thousand years ago, the importance of dietary factors in the gene­ sis of these diseases was more widely recognized from the eighteenth century onwards and it was not until this century that the chemical structure of these factors was determined and the substances themselves synthesized. As the science of biochemistry has developed it has been found that the clinical manifestations of vitamin deficiency follow derangement of multiple metabolic functions. The majority of the vitamins in fact form specific co-en­ zymes in various chemical processes but at least one is converted within the body into a hormone. The commercial extraction and synthesis of the vitamins, which began mainly in the 1930S and 1940s, produced adequate quantities for a relief of vitamin detlciency diseases. The use of vitamins then became fashionable and dramatic cures were claimed for an ever increasing number of diseases.

A Guide to the Vitamins: Their Role in Health and Disease

John Marks

This is the fourth volume of Standard Operating Procedures (SOPs) compiled from documents prepared in these laboratories in part fulfilment of the requirements of various Good Laboratory Practice (GLP) regulations and guidelines. SOPs have now become an everyday feature of work in most industrial and contract toxicology laboratories. They provide a written definition of the mechanics of unit operations which together comprise the framework for experiments in safety evaluation. Metabolic studies and analytical chemistry are closely linked to toxicology since they embody essential aspects of the overall assessment of product safety. Some authorities consider certain parts of these subjects to be outwith the scope of the GLP requirements but for the reasons stated this is contrary to our own view. We have tried where possible to define in SOP format for use in our own laboratories the unit operations involved in these disciplines and they form the basis of this volume. Some relevant material from previous volumes has been brought together in updated form and is also presented here for completeness. Dr I P Sword Managing Director Inveresk Research International Musselburgh EH21 7UB Scotland ix Introduction GENERAL 1. The Food and Drug Administration of the US Government published its Good Laboratory Practice Regulations for Non-Clinical Laboratory Studies in the Federal Register (22 December 1978). The Regulations are the culmin ation of a number of years of investigation into the standards to which safety evaluation studies were performed in laboratories in the USA.

Standard Operating Procedures Analytical Chemistry and Metabolism

A. W. Waddell I. P. Sword

This book is designed for use by medical students, nurses, young practitioners, internists, family physicians and all those initially involved with the problem of diagnostics. It is struc tured to provide a concise logical approach to the diagnosis of common illness and disorders in adults. The elucidation of an illness cause is not easy for the inexperienced. Although text books and guidance notes can be referred to for clarification of assembled thought - once a medical history has been taken - a system-orientated reference guide has considerable value for aiding and checking the logic of diagnosis. It is hoped that this book will fulfil that purpose. It could not have been written without the help of R. G. Brackenridge's Essential Medicine (1979, MTP, Lancaster, England), and J. Fry's Common Diseases (1979, MTP, Lancaster, England), to which the reader is referred and to which generous acknow ledgement is made. The tables of Differential Diagnosis that follow Chapters 3-7 are adapted from some that have appeared in Handbook of Differential Diagnosis, vols 1-3, published by Rocom Press, Hoffman La Roche Inc. , New Jersey, 1968-1974 - an invaluable publication now unfortun ately out of print, and permission to do so is gratefully apprec- 7 8 DIFFERENTIAL DIAGNOSIS iated. Finally without the stimulus and encouragement of Mr David Bloomer (MTP) and the particular assistance of Mrs J. C. Robinson, this book would never have been written. ALEXANDER D. G.

Differential Diagnosis: A guide to symptoms and signs of common diseases and disorders, presented in systematic form

A.D.G. Gunn

The Health Care Manual: A Family Guide to Self-Care and Home Medicines

John, Fry

This book provides instruction in applying basic treatment strategies to patient care. Emphasis is placed on teachi. ng diagnostic skills, and especially, the therapeutic management of emotionally disturbed patients. This book is intended as a companion text to Basic Psychopathology: A Programmed Text, whi. ch focuses more on teaching the description and observational skills for diagnosing common psychopathologic syn- dromes. Basic Psychotherapeutics gives pragmatic suggestions for treating a variety of psychopathologic disorders, many of which are newly classi- fied in the Diagnostic Statistical Manual - III (DSM-II1) published by The American Psychiatric Association. We have adopted the terminology and many, but not all, of the diagnosti. c criteria used in DSM-III. The treatment recommendations proposed are eclectic in nature and the infor- mation presented is non-theoretical and patient centered. Basic Psychotherapeutics is divided into three parts. The first re- views basic data collection procedures and treatment skills; it includes chapters on interviewing, the mental status examination and pharmaco- logic, psychologic and behavioral therapy. The next section includes chapters on commonly encountered psychiatric syndromes such as schiz- ophrenic, affective and anxiety disorders. The final chapters are pre- sentations of special clinical interest, such as the management of suicidal patients, psychiatric emergencies, treating the dying patient and his family, and others.

Basic Psychotherapeutics: A Programmed Text

C. W. Johnson J. R. Snibbe Leonard A. Evans

When my colleagues and I began the task of assembling this volume, several difficult questions arose: For whom were we writing? Was the purpose to eluci date psychiatric or medical presentation? Should references reflect specific to pical areas, or lead the reader to a more general view of a particular topic? Would a symptom or system approach best serve the reader? Should the volume cover a few areas in detail, or attempt to survey a larger area of knowledge? The present text reflects an attempt to answer these questions. It is designed for the student of medicine who desires a broader understanding of those medi cal illnesses that produce psychiatric aberration. We hope it will be of assis tance to the medical student or house officer studying medicine, neurology, family practice, pediatrics, or psychiatry; as well as to the practicing clinician who wishes a refresher on this subject or a reference for his library. The text is intended to strike a useful balance between medicine and psychiatry by provid ing a list of differentials for specific symptoms or conditions, as well as sugges tions for medical evaluation. References have been chosen which we hope will assist the reader in further study. We have attempted to diversify them and list a spectrum of articles that deal with both academic and practical treatment considerations. The initial volume is divided into four sections that address both a symptom and system approach.

Psychiatric Presentations of Medical Illness: Somatopsychic Disorders

Richard C.W. Hall

This book is an exploration of some of the psychological and so cial-psychological factors that have created barriers between women. Particular attention is paid to the daughter-mother relationship. The content is based on psychotherapy material, test results and conversations with patients and non-patients across a wide age span. I acquired the material in my various roles as a clinician, researcher and theorist-and, always, as a woman, with whatever special biases and special understandings that might involve. Because much of the book deals with the development of wom en's difficulties in relationships with other women, the emphasis will often be on how the growing daughter feels in her relationship with her mother. The mother's feelings will be discussed very little for two reasons: to limit the scope of this book and because much of what applies to the daughter also applies to the mother. It is often due to her own experiences as a daughter that the mother encounters difficulty in rearing her own daughter or feeling com fortable about her ability to do so. But it is important for the reader to keep in mind throughout the book that child-rearing is a frighten ing, difficult task at least part of the time for virtually every mother. In any long-term relationship, one begins to experience one's own needs, and it is simply human to wish that the other person in the relationship (even an infant or young child) would meet those needs.

Barriers Between Women

Self-Help

Paula J. Caplan

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