In the era of Evidence Based Medicine, health professionals are required to fully understand design, analysis and interpretation of the results of research. Furthermore, they should be able to assess the needs of their communities and respond accordingly. To achieve these goals, clinicians need to be familiar with the basic concepts of epidemiology and biostatistics. But epidemiology is more than "the study of" Its application and practice are essential to address public health issues. That is why this book provides not only the theory, but also the opportunity of applying it in practice. In fact, each chapter presents one or more specific examples on how to perform an epidemiological or statistical data analysis and includes download access to the software and databases, giving the reader the possibility of replicating the analyses described. The final purpose is, therefore, to introduce epidemiologic and biostatistical methods as applied to clinical research, and to develop proficiency with computer software for performing the analysis of clinical datasets.

Applied Epidemiology and Biostatistics

Science & Math

Biological Sciences

SEEd Medical Publishers

Increased caloric intake, increased refined carbohydrate consumption, and physical inactivity have led to an explosion in the worldwide incidence of abdominal obesity and the emerging epidemic of insulin resistance, resulting in an increase of metabolic syndrome. Physicians can use the metabolic syndrome concept to guide focused lifestyle changes, lower blood pressure goals, and earlier intervention with aspirin, LDL-lowering drugs, and perhaps insulin-sensitizing medications. The comprehensive ABCDE approach presented in this book provides a memory tool for use in everyday clinical practice. In this unique, easy-to-read text, the 17 most important clinical trials in the field of the metabolic syndrome are presented, that every clinician should know.

Metabolic Syndrome: From Risk Factors to Management

Medical Books

Blaha, Michael

Tota-Maharaj, Rajesh

Medicine

Economic issues related to the health sector have been gaining much attention in recent years, and the challenge of providing quality and comprehensive health care to a growing population has become increasingly complex. This book’s aim is to introduce readers to basic principles of economics and to a set of analytical tools of economic evaluations and their application in the health sector. The most important evaluation techniques are explained by examples: cost-minimization analysis, cost-effectiveness analysis, cost-utility analysis and cost-benefit analysis.

Pharmacoeconomics: Principles and Practice

Business & Money

Pradelli, Lorenzo

Wertheimer, Albert

Industries

In Parkinson’s disease, the past half-century of research has brought many fascinating advances in treatment. Proper identification and treatment of both motor and non-motor symptoms lead to a better overall quality of life, reducing stress incurred by both patient and caregiver. This book provides a comprehensive description of current treatment options for patients with Parkinson’s disease.

Parkinson's Disease: A Guide to Medical Treatment

Health, Fitness & Dieting

Carranza, Michael

Snyder, Madeline R.

Davenport Shaw, Jessica

Zesiewicz, Theresa A.

Diseases & Physical Ailments

The arena of multiple sclerosis (MS) treatment has changed substantially over the past 20 years. Now nine different agents are approved for use in MS with several different routes of administration, safety characteristics and efficacy profiles. For the clinician and patient the availability of agents means greater flexibility and chances of disease control. However the expansion of options has also made the treatment of MS an increasingly complex field. This book is intended to help the general neurologist, internist and pharmaceutical industry agent to quickly become familiar with the current and future options for treating relapsing forms of MS.

Multiple Sclerosis: A Guide to Pharmacologic Treatment

Ontaneda, Daniel

The definition of Market Access was first reported by the World Trade Organization as “to open markets for trade and improve transparency, reciprocity, and non-discrimination in international trade”. Pharmaceutical Market Access is different and it could be defined as achieving the optimal price for a product or service and/or the maximum reimbursement for the approved target population with no restrictions on funding for the medical technology. By the way, Market Access is not only the market authorization, but it also includes overlapping activities like pricing, health technology assessment, formulary, and reimbursement. Market Access is one of the most important activities for pharmaceutical companies and emerging countries represent an important opportunity for launching new products. It was reported that the Compounded Average Growth Rate (CAGR) was 6.0% in the period 2011-2017, and expected sales exceeding 1.1 trillion USD by 2017 for emerging countries. Furthermore, CAGR 2008-2012 for recently launched pharmaceuticals were 9.8% for emerging countries and 1.5% for the top 8 developed countries. The Market Access processes in the most important emerging countries in the selected regions are defined in this book with the aim to help local experts, local government officers, headquarter managements, and everyone who want to learn more about healthcare system and health policies pathways of Market Access, mapping and structure of decision makers, challenges and catalyzers for Market Access in the emerging countries.

Pharmaceutical Market Access in Emerging Markets

Schweiger, Dr Arturo Dr

Wong, Kally

Leong, Dr Debra Dr

Patient reported outcomes (PROs) are a measurement based on a report that comes directly from the patient about the status of their health condition without amendment or interpretation of the patient’s response by a clinician or anyone else. Valid and reliable PRO instruments are able to provide a standardized, quantifiable measure of treatment benefit, upon which the outcomes of interventions and treatment effect from the patient’s perspective can be judged. In some instances, PROs provide the best evidence of a treatment’s effectiveness, for example when evaluating treatments for pain, gastrointestinal and urological symptoms, or psychological well-being. This book aims to provide an overview of PRO applications, methodology and validation in order to help reader approach this measurement that are playing an increasingly central role in drug development decision making.

Patient Reported Outcomes: An overview

Muehlhausen, Willie

Nixon, Annabel

Wild, Diane

Administration & Medicine Economics

Elementi di biostatistica ed epidemiologia clinica per l’analisi degli studi osservazionali (Italian Edition)

Tripepi, Giovanni

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