Drug Design and Discovery in Alzheimer’s Disease includes expert reviews of recent developments in Alzheimer's disease (AD) and neurodegenerative disease research. Originally published by Bentham as Frontiers in Drug Design and Discovery, Volume 6and now distributed by Elsevier, this compilation of the sixteen articles, written by leading global researchers, focuses on key developments in the understanding of the disease at molecular levels, identification and validation of molecular targets, as well as innovative approaches towards drug discovery, development, and delivery. Beginning with an overview of AD pharmacotherapy and existing blockbuster drugs, the reviews cover the potential of both natural and synthetic small molecules; the role of cholinesterases in the on-set and progression of AD and their inhibition; the role of beta-site APP clearing enzyme-1 (BACE-1) in the production of β-amyloid proteins, one of the key reasons of the progression of AD; and other targets identified for AD drug discovery.

Drug Design and Discovery in Alzheimer’s Disease

Business & Money

Atta-Ur-Rahman

Industries

Bentham Science Publishers

Originally published by Bentham and now distributed by Elsevier, Recent Advances in Medicinal Chemistry, Volume 1 covers leading-edge research and recent developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, drug targets, and natural product research and structure-activity relationship studies. The fourteen updated reviews include unique experimental data and references, and each article highlights an important topic in current medicinal chemistry research. Topics covered include: aureolic acid group of anti-cancer antibiotics and non-steroidal anti-inflammatory drugs; aromatase inhibitors in adjuvant endocrine treatment of early-stage breast cancer in postmenopausal women; Rho GTPases and statins in targeting and developing therapies for tumors; and more.Edited and written by leading experts in medicinal chemistry researchReviews recent advances in the field, including the characterization of inorganic nanomaterials as therapeutic vehiclesCovers a variety of topical areas, such as HPLC and in the analysis of tricyclic antidepressants in biological samples, and tannins and their influence on health

Recent Advances in Medicinal Chemistry, Volume 1

Science & Math

Biological Sciences

The inhibition of angiogenesis is an effective mechanism of slowing down tumor growth and malignancies. The process of induction or pro-angiogenesis is highly desirable for the treatment of cardiovascular diseases, wound healing disorders, and more. Efforts to understand the molecular basis, both for inhibition and induction, have yielded fascinating results. Originally published by Bentham and now distributed by Elsevier, Anti-Angiogenesis Drug Discovery and Development, Volume 2 is an compilation of well-written reviews on various aspects of the anti-angiogenesis process. These reviews have been contributed by leading practitioners in drug discovery science and highlight the major developments in this exciting field in the last two decades. These reader-friendly chapters cover topics of great scientific importance, many of which are considered significant medical breakthroughs, making this book excellent reading both for the novice as well as for expert medicinal chemists and clinicians.

Anti-Angiogenesis Drug Discovery and Development: Volume 2

The spleen is an organ responsible for many biological functions, such as immunological defense, the removal of foreign particles from the blood stream, the metabolism of bilirubins, lipids and several amino acids, the control of the number and maturity of blood leukocytes and platelets and haematopoesis. This book is a collection of medical methods written exclusively to show the spleen in relation to basic sciences (anatomy and physiology) and related clinical practice and is a useful resource for clinical physicians, haematologists, oncologists, general surgeons, oncologic surgeons, trauma surgeons, resident physicians and medical students.

Spleen

Medical Books

Petroianu, Andy

Basic Sciences

The State of the Science in Universal Design: Emerging Research and Developments

Maisel, Jordana L.

Self-Help

The Stokes phenomenon refers to the emergence of jump discontinuities in asymptotic expansions at specific rays in the complex plane. This book presents a radical theory for the phenomenon by introducing the concept of regularization. Two methods of regul

The Stokes Phenomenon, Borel Summation and Mellin-Barnes Regularisation

Kowalenko, Victor

Mathematics

This e-book presents recent advances in research in the field of particulate systems. A comprehensive background on operations involving particulate materials with a didactic approach is illustrated. Fundamentals and applications in a variety of multi-ph

Transport Phenomena in Particulate Systems

Freire, José Teixeira

Chemistry

Advances in Organic Synthesisis a book series devoted to the latest advances in synthetic approaches towards challenging structures. It presents comprehensive articles written by eminent authorities on different synthetic approaches to selected target molecules and new methods developed to achieve specific synthetic transformations. Contributions are written by eminent scientists and each volume is edited by an authority in the field.Advances in Organic Synthesisis essential for all organic chemists in the academia and industry who wish to keep abreast of rapid and important developments in the field.

Advances in Organic Synthesis: Volume 6

Rahman, Atta-Ur

Genome science or genomics is essential to advancing knowledge in the fields of biology and medicine. Specifically, researchers learn about the molecular biology behind genetic expression in living organisms and related methods of treating human genetic diseases (including gene therapy). "Advances in Genome Science" is an book series which provides a multi-disciplinary view of some of the latest developments in genome research, allowing readers to capture the essentiality and diversity of genomics in contemporary science.

Changing Views on Living Organisms (Advances in Genome Science)

Neri, Christian

Evolution

Oxynitride thin film technology is rapidly impacting a broad spectrum of applications, ranging from decorative functions (through optoelectronics) to corrosion resistance. Developing a better understanding of the relationships between deposition processes, structure and composition of the deposited films is critical to the continued evolution of these applications. This book provides valuable information about the process modeling, fabrication and characterization of metallic oxynitride-based thin films produced by reactive sputtering and some related deposition processes. Its contents are spread in twelve main and concise chapters through which the book thoroughly reviews the bases of oxynitride thin film technology and deposition processes, sputtering processes and the resulting behaviors of these oxynitride thin films. More importantly, the solutions for the growth of oxynitride technology are given in detail with an emphasis on some particular compounds. This is a valuable resource for academic learners studying materials science and industrial coaters, who are concerned not only about fundamental aspects of oxynitride synthesis, but also by their innate material characteristics.

Metallic Oxynitride Thin Films by Reactive Sputtering and Related Deposition Methods: Process, Properties and Applications

Engineering & Transportation

Vaz, Filipe

Engineering

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