Since exposure to hazardous substances, commonplace in the modern industrial environment, can lead to adverse effects on health, statutory limits are established for the levels of such substances in the workplace air and of the substances themselves or their metabolites in the body fluids of workers. Therefore reliable analytical methods are required to determine the levels of such substances in air and in body fluids (usually blood or urine).   The Analytical Chemistry Group of the Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has established new methods and standardized old ones for the biological monitoring of numerous industrial chemicals. The analytical reliability and reproducibility of each of the methods has been determined by the author and confirmed by at least one examiner. The methods are therefore suitable for checking adherence to statutory limits such as the German BAT values (Biological Tolerance Values for Working Materials) and the American BEI values (Biological Exposure Indices) and for reliable detection of dangerous substances in the tissues of individual workers.

Analyses of Hazardous Substances in Biological Materials, Vol. 3

Science & Math

Schaller, Karl-Heinz

Angerer, Jürgen

Biological Sciences

Wiley-VCH

Biological monitoring has proved extremely valuable in assessing the health risk of persons exposed to hazardous chemical substances in the environment or at the workplace. The chemical compounds are generally determined in body fluids. They are present in trace or ultratrace concentrations. Specific and extremely sensitive methods of chemical analysis are necessary to separate these substances from the biological matrix and to determine them precisely.  This volume contains 12 standardized analytical methods. All methods are suitable for routine use. They meet exceptionally high standards of reliability and reproducibility and are in accordance with 'Good Laboratory Practice'. Considerable emphasis is placed on sample collection methods and on analytical quality control. One gereral chapter introduces biological monitoring using ICP-spectroscopy.

Analyses of Hazardous Substances in Biological Materials (Volume 5)

Schaller, K. H.

Angerer, Edited by: J.

Chemistry

<p>Biological monitoring has proved extremely valuable in assessing the health risk of persons exposed to hazardous chemical substances in the environment or at the workplace. The chemical compounds are generally determined in body fluids. They are present in trace or ultratrace concentrations. Specific and extremely sensitive methods of chemical analysis are necessary to separate these substances from the biological matrix and to determine them precisely.<br><br> All methods are suitable for routine use. They meet exceptionally high standards of reliability and reproducibility and are in accordance with 'Good Laboratory Practice'. Considerable emphasis is placed on sample collection methods and on analytical quality control.</p>

Analyses of Hazardous Substances in Biological Materials, Volume 7

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