The Elusive Magic Bullet

Mann,John

Medical Books

Oxford University Press

In his exciting new book, John Mann, author of the highly successful Murder, Magic and Medicine, reveals the history of the drugs that are so commonplace today in the treatment of disease. While we can now treat so many of these illnesses, the side-effects caused by many of these treatmentscan be severe, and even more worrying -- the bacteria are now becoming more resistant to the drugs (the so-called 'superbugs'). Scientists are also faced with a massive challenge in developing drugs that can effectively treat HIV, ebola, and many forms of cancer, but without the terribleside-effects of such treatments as chemotherapy or AZT -- this is the quest for the `magic bullet.'The book starts with a history of drug development, introducing us to some of the fascinating characters whose work so influenced the search for these drugs. Leading up to the present day, and the exciting advances being made within molecular biology, the book provides a lively, and fascinatingintroduction for non-scientists to one of the most exciting fields of activity within modern medicine.

The Elusive Magic Bullet: The Search for the Perfect Drug

Pharmacology

People have always been curious about the plants and animals with which they coexist. Primitive cultures identified edible and poisonous plants largely by trial and error, and then used them for hunting, executions, euthanasia, and magico-religious rites, as well as for their medicinal properties. In this fascinating book, John Mann investigates the evolution of modern medicine from its roots in folk medicine, and reveals the continuing importance of natural plant and animal products, many of which remain undiscovered but under threat by the wholesale destruction of the Earth's wild places. In this new edition, he has updated the material to include discussion of the background to some of the most talked about drugs of recent years, including Prozac and Viagra.

Murder, Magic, and Medicine

Health, Fitness & Dieting

Alternative Medicine

This absorbing account of the evolution of modern medicine from its roots in folk culture will entertain and inform both scientists and general readers alike. It explains the chemical basis of modern pharmacology, and provides a fascinating description of the use and abuse of natural products in various societies through the ages and how this largely trial-and-error process has led to the development of many of the drugs we now take for granted. Primitive cultures especially identified a wealth of edible and poisonous plants, and refined their use in practices related to hunting, healing, magic, religion, and warfare. Today, this heritage can be linked to the origin of such modern-day substances as hemlock and other notorious poisons, as well as to a range of psychoactive drugs like cocaine and LSD, and to beneficial pharmaceuticals including quinine, penicillin, and AZT. However many plant and animal species still remain undiscovered, and as the author notes, much native folk medicine has yet to be investigated. With the rapid destruction of many of the earth's natural resources, this book is particularly timely as these potentially valuable sources could be lost forever.

This introductory text describes and explains the chemistry involved in the biosynthesis of secondary metabolites. The book emphasizes the pharmacological and toxicological significance of the compounds, and the final chapter reviews their ecological role. Suggestions for further reading are provided.

Chemical Aspects of Biosynthesis (Oxford Chemistry Primers)

Reference

Words, Language & Grammar

This concise text provides the perfect introduction to the chemistry involved in the biosynthesis of natural products. It straightforwardly explains the connections between primary and secondary metabolites, outlines the chemistry mediated by major enzyme cofactors, and describes methods for the elucidation of biosynthetic pathways. The different classes of secondary metabolites are detailed with an emphasis on the pharmacology and toxicology of the various compounds. The book concludes with an examination of the ecological significance of a wide variety of natural products. Undergraduates in organic chemistry and bio-organic chemistry courses will appreciate the readability and cogency of this much-needed text.

Science & Math

Biological Sciences

This absorbing account of the evolution of modern medicine from its roots in folk medicine will entertain and inform both scientist and general reader alike. It explains the chemical basis of pharmacology, and provides a fascinating description of how the use and abuse of natural products in various societies throughout the ages has led to the development of many of the drugs we now take for granted.

Secrets of life extension: A practical guide for the use of life-extension therapies

Bantam]

Students of the light;: An educational odyssey

Grossman Publishers

This text is part of the Biochemical and Medicinal Chemistry Series Series Editor: John Mann, Professor of Organic Chemistry, University of Reading The aim of this series of short textbooks is to present full accounts of topics which are at the interface of chemistry and biology, from medicinal chemistry to molecular biology. The topics chosen for inclusion are popular subjects for upper-level undergraduate and postgraduate modular courses, and yet they receive inadequate coverage in traditional textbooks of organic chemistry and of biochemistry. Each text in the series provides a concise and up to date introduction to its subject in an attractive format. Antibiotics are among the most prescribed drugs in the world today, and since their development and commercialization in the early part of this century, they have saved countless millions of lives. Combating bacterial infection has resulted in the development of compounds which include the penecillins, cephalosporins, aminoglycosides and tetracyclins. This concise and up to date textbook uses a wide range of examples to describes the structure, mechanisms of action, synthesis and biosynthetic pathways of the major classes of antibiotics. A serious problem today is the development of microorganisms that are resistant to these 'traditional' antibiotics. This important area is described, with an account of bacterial resistance mechanisms, and the latest advances aimed at overcoming these problems. This textbook is suitable for upper-level undergraduate courses given to chemists, biochemists, microbiologists, pharmacologists and medical students. Postgradates and entrants to the pharmaceutical industry will find it an invaluable introduction to the subject.

Bacteria and Antibacterial Agents (Biochemical and Medicinal Chemistry Series)

Crabbe, M. James C.

See the best price to sell, buy, or rent books by Mann,John. BookScouter helps to compare book prices from 25+ online bookstores and 30+ buyback vendors with a single search.

Books by Mann,John

See the best price to sell, buy, or rent books by Mann,John. BookScouter helps to compare book prices from 25+ online bookstores and 30+ buyback vendors with a single search.

The Elusive Magic Bullet

The Elusive Magic Bullet: The Search for the Perfect Drug

Murder, Magic, and Medicine

Murder, Magic, and Medicine

Chemical Aspects of Biosynthesis (Oxford Chemistry Primers)

Chemical Aspects of Biosynthesis (Oxford Chemistry Primers)

Murder, Magic, and Medicine

Secrets of life extension: A practical guide for the use of life-extension therapies

Students of the light;: An educational odyssey

Bacteria and Antibacterial Agents (Biochemical and Medicinal Chemistry Series)