An up-to-date overview of the field of connectomics, introducing concepts and mechanisms underlying brain network change at different stages. The human brain undergoes massive changes during its development, from early childhood and the teenage years to adulthood and old age. Across a wide range of species, from C. elegans and fruit flies to mice, monkeys, and humans, information about brain connectivity (connectomes) at different stages is now becoming available. New approaches in network neuroscience can be used to analyze the topological, spatial, and dynamical organization of such connectomes. In Changing Connectomes, Marcus Kaiser provides an up-to-date overview of the field of connectomics and introduces concepts and mechanisms underlying brain network changes during evolution and development. Drawing on a range of results from experimental, clinical, and computational studies, Kaiser describes changes during healthy brain maturation and during brain network disorders (including such neurodevelopmental conditions as schizophrenia and depression), brain injury, and neurodegenerative disorders including dementia. He argues that brain stimulation is an area where understanding connectome development could help in assessing long-term effects of interventions. Changing Connectomes is a suitable starting point for researchers who are new to the field of connectomics, and also for researchers who are interested in the link between brain network organization and brain and cognitive development in health and disease. Matlab/Octave code examples available at the MIT Press website will allow computational neuroscience researchers to understand and extend the shown mechanisms of connectome development.

Changing Connectomes: Evolution, Development, and Dynamics in Network Neuroscience

Science & Math

Kaiser, Marcus

Biological Sciences

The MIT Press

How is space shaped, what elements are employed in that process, and how are the components that shape space defined? The fifth volume of the SCALE series, "Furnish | Zone", treats the relationship between building typology, building structure, spatial composition, and interior architecture. It reveals how formulating the task relates to the list of requirements and explains the relationship between the shell and finishing the interior. "Furnish | Zone" includes an introduction to the topic of space and chapters on dressing and cladding, separating, and adapting. Structured according to interiors elements, it effectively covers all the tasks of interior architecture and provides a valuable tool for designing everything from store fixtures to office spaces. Connections for walls, ceilings, and floors are explained in detail and supplemented by comments on selected projects. In addition, "Furnish | Zone" shows the potential added value of carefully considering the design of spaces, for example, in terms of materials and lighting, or by making spaces and functions flexible.

Furnishing | Zoning: Spaces, Materials, Fit-out (Scale, 4)

Arts & Photography

Herrmann, Eva

Katz, Tobias

Architecture

Birkhauser

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Books by Kaiser, Marcus