Bioconductor Case Studies

Science & Math

Huber, Wolfgang

Gentleman, Robert

Hahne, Florian

Biological Sciences

Springer

Bioconductor software has become a standard tool for the analysis and comprehension of data from high-throughput genomics experiments. Its application spans a broad field of technologies used in contemporary molecular biology. In this volume, the authors present a collection of cases to apply Bioconductor tools in the analysis of microarray gene expression data. Topics covered include: (1) import and preprocessing of data from various sources; (2) statistical modeling of differential gene expression; (3) biological metadata; (4) application of graphs and graph rendering; (5) machine learning for clustering and classification problems; (6) gene set enrichment analysis. Each chapter of this book describes an analysis of real data using hands-on example driven approaches. Short exercises help in the learning process and invite more advanced considerations of key topics. The book is a dynamic document. All the code shown can be executed on a local computer, and readers are able to reproduce every computation, figure, and table.

Bioconductor Case Studies (Use R!)

Computers & Technology

Falcon, Seth

Computer Science

Book by Kidd, Parris M., Huber, Wolfgang

Living With the AIDS Virus: A Strategy for Long-Term Survival

Medical Books

Kidd, Parris M.

Medicine

Hk Biomedical-Educational Div

If you are a biologist and want to get the best out of the powerful methods of modern computational statistics, this is your book. You can visualize and analyze your own data, apply unsupervised and supervised learning, integrate datasets, apply hypothesis testing, and make publication-quality figures using the power of R/Bioconductor and ggplot2. This book will teach you 'cooking from scratch', from raw data to beautiful illuminating output, as you learn to write your own scripts in the R language and to use advanced statistics packages from CRAN and Bioconductor. It covers a broad range of basic and advanced topics important in the analysis of high-throughput biological data, including principal component analysis and multidimensional scaling, clustering, multiple testing, unsupervised and supervised learning, resampling, the pitfalls of experimental design, and power simulations using Monte Carlo, and it even reaches networks, trees, spatial statistics, image data, and microbial ecology. Using a minimum of mathematical notation, it builds understanding from well-chosen examples, simulation, visualization, and above all hands-on interaction with data and code.

Modern Statistics for Modern Biology

Holmes, Susan

Cambridge University Press

If you are a biologist and want to get the best out of the powerful methods of modern computational statistics, this is your book. You can visualize and analyze your own data, apply unsupervised and supervised learning, integrate datasets, apply hypothesis testing, and make publication-quality figures using the power of R/Bioconductor and ggplot2. This book will teach you 'cooking from scratch', from raw data to beautiful illuminating output, as you learn to write your own scripts in the R language and to use advanced statistics packages from CRAN and Bioconductor. It covers a broad range of basic and advanced topics important in the analysis of high-throughput biological data, including principal component analysis and multidimensional scaling, clustering, multiple testing, unsupervised and supervised learning, resampling, the pitfalls of experimental design, and power simulations using Monte Carlo, and it even reaches networks, trees, spatial statistics, image data, and microbial ecology. Using a minimum of mathematical notation, it builds understanding from well-chosen examples, simulation, visualization, and above all hands-on interaction with data and code.

Ethics: The Fundamental Questions of Our Lives

In the twenty-first century the basic questions of ethics are no longer the abstract terms of ethical theory, but the concrete and burning issues related to the influence of life sciences, the impact of a globalized economy, and the consequences of present decisions for the future of humankind. Ethics: The Fundamental Questions of Our Lives analyzes twenty ethical issues that address education and culture, labor and economy, the environment and sustainability, democracy and cosmopolitanism, peace and war, and life and death. Each chapter describes a concrete example showing the relevance of the fundamental ethical question, then provides an explanation of how one can think through possible responses and reactions. Huber emphasizes the connections between personal, professional, and institutional ethics and demonstrates how human relationships lie at the center of our ethical lives. His aim is to articulate a theology of what he calls "responsible freedom" that transcends individualistic self-realization and includes communal obligations.

Religion & Spirituality

Georgetown University Press

In the twenty-first century the basic questions of ethics are no longer the abstract terms of ethical theory, but the concrete and burning issues related to the influence of life sciences, the impact of a globalized economy, and the consequences of present decisions for the future of humankind. Ethics: The Fundamental Questions of Our Lives analyzes twenty ethical issues that address education and culture, labor and economy, the environment and sustainability, democracy and cosmopolitanism, peace and war, and life and death. Each chapter describes a concrete example showing the relevance of the fundamental ethical question, then provides an explanation of how one can think through possible responses and reactions. Huber emphasizes the connections between personal, professional, and institutional ethics and demonstrates how human relationships lie at the center of our ethical lives. His aim is to articulate a theology of what he calls "responsible freedom" that transcends individualistic self-realization and includes communal obligations.

Ethik: Die Grundfragen unseres Lebens von der Geburt bis zum Tod

Beck C. H.

Position beziehen: Das Ende der Beliebigkeit

Johannis Verlag

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Books by Huber, Wolfgang