Principles of Drug Therapy, Second Edition provides comprehensive coverage of current drug therapy in neurology while providing the background information that neurologists and other clinicians need to understand its rationale. The range of new drugs available for treatment of neurological disorders is expanding rapidly along with rapid advances in the neurosciences that are uncovering disease mechanisms. Although there are many sources of drug information, most are limited to basic information about indications, dose and side effects. However the complexity of the nervous system is enormous and the information needed to understand drug effects is accordingly often not readily available in a single source. The book addresses that issue by presenting 18 focused, disease-related chapters by authors who are expert clinical sub-specialists as well as experts on drug therapy. The first chapter on fundamentals of drug therapy in neurology provides a readable synopsis of how the classic pharmacology concepts such as pharmacodynamics and pharmacokinetics are related to therapy in neurology. This section also discusses the pathogenesis of potentially serious side effects such as skin rashes and liver disorders, and the role of pharmacogenetics in both drug effect and side effects. Outstanding chapters on movement disorders, epilepsy, and headaches cover major areas of drug treatment in neurology practice. Additional chapters cover stroke, increased intracranial pressure in the intensive care unit, dementia, multiple sclerosis, spinal cord injury and spasticity, neuromuscular disorders and pain. Sleep, central nervous system infections and HIV, and drug intoxications are also covered. Areas of special interest to child neurologists covered in the book include treatment of genetic metabolic disorders and use of stimulants and other medications for childhood cognitive disorders. An excellent chapter is also provided on drug treatment of psychiatric disorders because of the important of psychiatric drugs in neurology practice. This edition has been completely re-written from the successful edition published in the 90s and enlarged commensurate with the exciting progress in treatment in neurology.

Principles of Drug Therapy in Neurology (Contemporary Neurology Series)

Medical Books

Gross, Robert A.

Johnston, Michael V.

Medicine

Oxford University Press

Product Description 
One of The Wall Street Journal's 10 best books of 2021In the year of the nation’s bicentennial, Robert A. Gross published The Minutemen and Their World, a paradigm-shaping study of Concord, Massachusetts, during the American Revolution. It won the prestigious Bancroft Prize and became a perennial bestseller. Forty years later, in this highly anticipated work, Gross returns to Concord and explores the meaning of an equally crucial moment in the American story: the rise of Transcendentalism.The Transcendentalists and Their World offers a fresh view of the thinkers whose outsize impact on philosophy and literature would spread from tiny Concord to all corners of the earth. Ralph Waldo Emerson, Henry David Thoreau, Nathaniel Hawthorne, and the Alcotts called this New England town home, and Thoreau drew on its life extensively in his classic Walden. But Concord from the 1820s through the 1840s was no pastoral place fit for poets and philosophers.The Transcendentalists and their neighbors lived through a transformative epoch of American life. A place of two thousand–plus souls in the antebellum era, Concord was a community in ferment, whose small, ordered society founded by Puritans and defended by Minutemen was dramatically unsettled through the expansive forces of capitalism and democracy and tightly integrated into the wider world. These changes challenged a world of inherited institutions and involuntary associations with a new premium on autonomy and choice. They exposed people to cosmopolitan currents of thought and endowed them with unparalleled opportunities. They fostered uncertainties, raised new hopes, stirred dreams of perfection, and created an audience for new ideas of individual freedom and democratic equality deeply resonant today.The Transcendentalists and Their World is both an intimate journey into the life of a community and a searching cultural study of major American writers as they plumbed the depths of the universe for spiritual truths and surveyed the rapidly changing contours of their own neighborhoods. It shows us familiar figures in American literature alongside their neighbors at every level of the social order, and it reveals how this common life in Concord entered powerfully into their works. No American community of the nineteenth century has been recovered so richly and with so acute an awareness of its place in the larger American story. 
 Review 
"Gross has delivered a second harvest of his career-long work. It is a measured, beautiful volume that brings warm life, accuracy, and complexity to local history, swooping between the bird’s-eye view and the tracery of many individual destinies . . . Absorbing . . . Illuminating." ―Mark Greif, The Atlantic"Concord is the subject of Robert Gross’s monumental The Transcendentalists and Their World, easily the most comprehensive work ever written about the town’s social history during the transcendentalist era . . . Gross’s historiography is patient, thorough, cumulative . . . Gross’s richly detailed account shows us how such a surprising conjunction of place and thought could occur." ―Randall Fuller, The Wall Street Journal"An astonishing feat of granular history, The Transcendentalists and Their World skillfully weaves into a range of interlocking narratives the material that Gross has unearthed in diaries, letters, newspapers and pamphlets . . . Each of [Gross’s] extended vignettes simultaneously reveals prodigious research, a deft eye for detail and a well-honed gift for storytelling . . . Surely [the] definitive history of Concord in this era." ―Mark Ford, Times Literary Supplement"Gross ably depicts how Concord shaped [Emerson and Thoreau], and how they also departed from town norms . . . It’s hard not to respect this labor of a lifetime. [Gross's] scholarship, based on research in many other libraries as well, is impeccable . . . An essential work on these towering figures of American literature." ―Dan Cryer, The Bos

The Transcendentalists and Their World

Biographies & Memoirs

Historical

Farrar. Straus and Giroux

Fusion Energy

Engineering & Transportation

Engineering

John Wiley&Sons

Winner of the Bancroft Prize 
The Minutemen and Their World, first published in 1976, is reissued now in a twenty-fifth anniversary edition with a new Foreword by Alan Taylor and a new Afterword by the author.
On April 19, 1775, the American Revolution began at the Old North Bridge in Concord, Massachusetts. The "shot heard round the world" catapulted this sleepy New England town into the midst of revolutionary fervor, and Concord went on to become the intellectual capital of the new republic. The town--future home to Emerson, Thoreau, and Hawthorne--soon came to symbolize devotion to liberty, intellectual freedom, and the stubborn integrity of rural life. In The Minutemen and Their World, Robert Gross has written a remarkably subtle and detailed reconstruction of the lives and community of this special place, and a compelling interpretation of the American Revolution as a social movement.

The Minutemen and Their World

Reference

Hill and Wang

In Debt to Shays takes a fresh perspective on the rebellion by challenging existing understandings of late eighteenth-century America and restoring the rebellion to its historical context

In Debt To Shay's: The Bicentennial of an Agrarian Rebellion (Colonial Society of Massachusetts)

History

Americas

Colonial Society of Massachusetts

Much Instruction from Little Reading: Books and Libraries in Thoreau's Concord

Amer Antiquarian Society

Printing, Politics, and the People: 1989 James Russell Wiggins Lecture (The James Russell Wiggins Lecture in the History of the Book in American Culture, 1989)

Winner of the Bancroft Prize\nThe Minutemen and Their World, first published in 1976, is reissued now in a revised and expanded edition with a new preface and afterword by the author.\nOn April 19, 1775, the American Revolution began at the Old North Bridge in Concord, Massachusetts. The “shot heard round the world” catapulted this sleepy New England town into the midst of revolutionary fervor, and Concord went on to become the intellectual capital of the new republic. The town―future home to Emerson, Thoreau, and Hawthorne―soon came to symbolize devotion to liberty, intellectual freedom, and the stubborn integrity of rural life.\nIn The Minutemen and Their World, Robert A. Gross has written a remarkably subtle and detailed reconstruction of the lives and community of this special place, and a compelling interpretation of the American Revolution as a social movement.

The Minutemen and Their World: (Revised and Expanded Edition)

Picador Paper

From the eminent and award-winning historian Robert A. Gross comes his long-awaited, immersive journey through Concord in the age of Emerson and Thoreau, The Transcendentalists and Their World.\nOne of The Wall Street Journal’s 10 Best Books of 2021\nWhy Concord? How did a small and seemingly quiet village in the hinterlands of Boston become, by popular reckoning, the birthplace of two revolutions―the American War of Independence that began with shots fired by the local Minutemen, and the American Renaissance of literature and thought that began with the Transcendentalists’ challenge to established pieties? In The Transcendentalists and Their World, the distinguished historian Robert A. Gross gives a rich and beautifully detailed account of the town that Ralph Waldo Emerson, Henry David Thoreau, Nathaniel Hawthorne, and the Alcotts called home. Their Concord, he shows, was primed for revolt, and was hardly a sleepy, bucolic place fit only for poets and philosophers.\nThe Transcendentalists and their neighbors lived in an age of transformation. A place of more than two thousand souls in the antebellum era, Concord was a community in ferment, one whose small, ordered society, founded by Puritans and defended by Minutemen, was dramatically unsettled by the expansive forces of capitalism and democracy while the town became more tightly integrated with the wider world. These changes posed a challenge to a society built on inherited institutions and involuntary associations as citizens placed a new premium on autonomy and choice. Concord was ripe for Emerson and Thoreau.\nThe Transcendentalists and Their World is both an intimate journey into the life of a town and a searching cultural study of major American writers as they plumbed the reaches of the universe for spiritual truths―and took stock of the rapidly changing contours of their surroundings. It shows us familiar literary figures alongside their neighbors―white and Black, devout and blasphemous, and situated at every level of the social order―and it reveals how this common life in Concord entered powerfully into their works. No American community has been recovered so richly and located so meaningfully within the larger American story.

Picador

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Books by Gross, Robert A.